2009 | 2008 | 2007 | 2006 | 2005 | 2004 | 2003 | 2002 | 2001 | 2000 | 1999 | 1998 | 1997 | 1996 | 1995 | 1994 | 1993 | 1992 | 1991 | 1990
Chebib M, Gavande N, Wong KY, Park A, Premoli I, Mewett KN, Allan RD, Duke RK, Johnston GAR and Hanrahan JR "Guanidino acids act as rho1 GABA-C receptor antagonists" Neurochemical Research, 2009, 34, 1704-1711 [PDF]
Chebib M, Hinton T, Schmid KL,Brinkworth D, Qian H, Matos S, Kim H-L, Abdel-Halim H, Kumar RJ, Johnston GAR and Hanrahan JR (2009) "Novel, potent and selective GABA-C antagonists inhibit myopia development and facilitate learning and memory", Journal of Pharmacology and Experimental Therapeutics, 328, 448-457 [PDF]
Fernandez SP, Nguyen M, Yow TT, Chu C, Johnston GAR, Hanrahan JR and Chebib M "The flavonoid glycosides, myricitrin, gossypin and naringin exert anxiolytic action in mice" Neurochemical Research, 2009, 34, 1867-1878 [PDF]
Hanrahan JR and Johnston GAR (2009) Synthesis of γ-aminobutyric acid analogues. In: Amino Acids, Peptides and Proteins in Organic Chemistry, Volume 1, Origins and synthesis of amino acids, Ed AB Hughes, Wiley VCH, Weinheim,, pp. 573-689
Hinton T and Johnston GAR "Anxiolytic and hypnotic drugs acting on ionotropic GABA receptors", Encyclopedia of Neuroscience, edited by MD Binder, N Hirokawa, and U Windhorst, Springer-Verlag, 2009, pp 154-159 [PDF]
Johnston GAR , Chebib M , Duke RK, Fernandez SP, Hanrahan JR , Hinton T and Mewett KN "Herbal products and ionotropic GABA receptors" New Encyclopedia of Neuroscience, edited by LR Squire, Elsevier, 2009, 4, 1095-1101 [PDF]
Locock KES, Johnston GAR and Allan RD, "GABA analogues derived from 4-aminocyclopent-1-enecarboxylic acid" Neurochemical Research, 2009, 34, 1698-1703 [PDF]
McIntosh JM, Absalom N, Chebib M, Elgoyhen AB, Vincler M "Alpha9 nicotinic acetylcholine receptors and the treatment of pain" Biochemical Pharmacology, 2009, 78, 693-702
Mewett KN, Fernandez SP, Pasricha AK, Pong A, Devenish SO, Chebib M, Johnston GAR, Hibbs DE and Hanrahan JR, "Synthesis and biological evaluation of flavan-3-ol derivatives as positive modulators of GABA-A receptors", Bioorganic & Medicinal Chemistry, 2009, 17, 7156–7173 [PDF]
Abdel-Halim H, Hanrahan JR, Hibbs DE, Johnston GAR and Chebib M "Amolecular basis for agonist and antagonist actions at GABA-Creceptors", Chemical Biology and Drug Design, 2008, 71,306-327 [PDF]
Carland JE, Johnston GAR and Chebib M "Relative impact of residuesat the intracellular and extracellular ends of the human GABA-C rho1receptor M2 domain on picrotoxinin activity", European Journal ofPharmacology, 2008, 580, 27-35 [PDF]
Fernandez SP, Mewett KN, Hanrahan JR, Chebib M, Johnston GAR, "Flavan-3-ol derivatives are positive modulators of GABA-A receptorswith higher efficacy for the alpha2 subtype and anxiolytic action inmice", Neuropharmacology, 2008, 55, 900-907 [PDF]
Hinton T, Chebib M.and Johnston GAR "Enantioselective actions of4-amino-3-hydroxybutanoic acid and(3-amino-2-hydroxypropyl)methylphosphinic acid at recombinant GABA-Creceptors", Bioorganic & Medicinal Chemistry Letters,2008, 18, 402-404 [PDF]
Hinton T and Johnston GAR "The role of GABA-A receptors inschizophrenia" Cell Science Reviews, 2008, 5, 180-194[PDF]
Kumar RJ, Chebib M, Hibbs DE, Kim H-L, Johnston GAR, Salam NK andHanrahan JR "Novel gamma-aminobutyric acid rho1 receptor antagonists;Synthesis, pharmacological activity and structure activityrelationships", Journal of Medicinal Chemistry, 2008,51, 3825-3840) [PDF]
Skilbeck KJ, Hinton T and Johnston GAR "Sex-differences andstress: effects on regional high and low affinity [3H]GABAbinding" Neurochemistry International, 2008, 52,1212-1219 [PDF]
Skillbeck KJ, O'Reilly JN, Johnston GAR and Hinton T"Antipsychotic drug administration differentially affects[3H]muscimol and [3H]flunitrazepam GABA-A receptorbinding sites" Progress in Neuro-Psychopharmacology &Biological Psychiatry, 2008, 32, 492-498 [PDF]
Chebib M, Hanrahan JR, Kumar RJ, Mewett KN, Morriss G, Wooller Sand Johnston GAR "(3-Aminocyclopentyl)methylphosphinic acids: NovelGABA-C receptor antagonists", Neuropharmacology, 2007,52, 779-787 [PDF]
Skilbeck KJ, O'Reilly JN, Johnston GAR and Hinton T. The effectsof antipsychotic drugs on GABA-A receptor binding depend on period ofdrug treatment and binding site examined .SchizophreniaResearch, 2007, 90, 76-80 [PDF]
Crittenden DL, Park, A, Qiu J, *Silverman RB, Duke RK, JohnstonGAR, **Jordan MJT and Chebib M 'Enantiomers of cis-constrained andflexible 2-substituted GABA analogues exert opposite effects atrecombinant GABA-C receptors' Bioorganic and MedicinalChemistry, 2006, 14, 447-455 [PDF]
Fernandez SP, *Wasowski C , *Loscalzo LM, Granger RE, JohnstonGAR, *Paladini AC and *Marder M 'Central nervous system depressantaction of flavonoid glycosides', European Journal ofPharmacology, 2006, 539, 168-176 [PDF]
Greenwood JR, Mewett KN, Allan RD, *Martin BO, *Pickering DS(2006) '3-hydroxypyridazine 1-oxides as carboxylate bioisosteres: anew series of subtype-selective AMPA receptoragonists'. Neuropharmacology, 51, 52-59
Hanrahan JR, Mewett KN, Chebib M, Matos S, Eliopoulos CT, Crean C,Kumar RJ, Burden P, and Johnston GAR 'Diastereoselective synthesis of(±)-(3-aminocyclopentanyl)alkylphosphinic acids,conformationally restricted analogues of GABA, Organic &Biomolecular Chemistry, 2006, 4, 2642 - 2649 [PDF]
Huang SH, Duke RK, Chebib M, Sasaki K, Wada K and Johnston GAR(2006) Mixed antagonistic effects of bilobalide at rho1 GABA-Creceptors, Neuroscience, 2006, 137, 607-617 [PDF]
Johnston GAR, Hanrahan JR, Chebib M, Duke RK and Mewett KN.Modulation of ionotropic GABA receptors by natural products of plantorigin, Adv. Pharmacol., 2006, 54, 285-316 [PDF]
Crittenden DL, Chebib M and **Jordan MJT 'Stabilization ofzwitterions in solution: GABA analogues' Journal of PhysicalChemistry A, 2005, 109, 4195-4201
Crittenden DL, Kumar RJ, Hanrahan JR, Chebib M and **Jordan MJT'Stabilization of zwitterions in solution: phosphinic and phosphonicacid GABA analogues' Journal of Physical Chemistry A, 2005,109, 8398-8409
*Gibbs ME and Johnston GAR 'Opposing roles for GABA-A and GABA-Creceptors in short-term memory formation in young chicks'Neuroscience, 2005, 131, 567-576 [PDF]
Granger RE, Campbell EL and Johnston GAR '(+) and (-)-Borneol:efficacious positive modulators of GABA action at human recombinantalpha1beta2gamma2L GABA-A receptors' Biochemical Pharmacology,2005, 69, 1101-1111 [PDF]
Hall BJ, Chebib M, Hanrahan JR and Johnston GAR'6-Methylflavanone, a more efficacious positive allosteric modulatorof gamma-aminobutyric acid (GABA) action at human recombinantalpha2beta2gamma2L than at alpha1beta2gamma2L and alpha1beta2 GABA-Areceptors expressed in Xenopus oocytes', European Journal ofPharmacology, 2005, 512, 97-104 [PDF]
Henderson JM, Schleimer S, Allbutt H, Dabholkar V, Abela D, JovicJ and Quinlivan M 'Behavioural effects of parafascicular thalamiclesions in an animal model of parkinsonism', Behavioural BrainResearch 2005, 162, 222-232
James ML, Fulton RR, Henderson DJ,Eberl S, Meikle SR,ThomsonS, Allan RD, Dolle F, Fulham MJ, and Kassiou M. Synthesis and invivo evaluation of a novel peripheral benzodiazepine receptor PETradioligand, Bioorganic & Medicinal Chemistry 2005,13, 6188-6194
Johnston GAR , GABA-A receptor channel pharmacology, CurrentPharmaceutical Design, 2005, 11, 1867-1885 [PDF]
Schleimer SB, Johnston GAR and Henderson JM 'Novel oral drugadministration in an animal model of chronic neuroleptic therapy 'Journal of Neuroscience Methods, 2005, 146, 159-164[PDF]
Allan RD, Greenwood J, **Hambley TW, Hanrahan JR, **HibbsDE, **Itani S, Tran HW and **Turner P. 'Studies on Pyridazine AzideCyclisation Reactions' Organic & Biomolecular Chemistry,2004, 2, 1782-1788
Campbell EL, Chebib M and Johnston GAR, 'The dietary flavonoidsapigenin and (-)-epigallocatechin gallate enhance the positivemodulation by diazepam of the activation by GABA of recombinantGABA-A receptors' Biochemical Pharmacology, 2004, 68,1631-1638 [PDF]
Carland JE, Moorhouse AJ, Barry PH, Johnston GAR and Chebib M'Charged residues at the 2' position of human GABA-C rho1 receptorsinvert ion selectivity and influence open state probability'Journal of Biological Chemistry, 2004, 279, 54153-54169[PDF]
Carland JE, *Moore AM, Hanrahan JR, Mewett KN, Duke RK, JohnstonGAR and Chebib M, 'Mutations of the 2' proline in the M2domain of the human GABA-C rho1 subunit alter agonist responses'Neuropharmacology, 2004, 46, 770-781 [PDF]
Chebib M, Hanrahan JR, Mewett KN, Duke RK and Johnston GAR,'Ionotropic GABA receptors as therapeutic targets for memory andsleep disorders' Annual Reports in Medicinal Chemistry, 2004,39, 13-23 [PDF]
Duje RK, Chebib M, **Hibbs DE, Mewett KN and Johnston GAR'Synthesis and resolution of 2-methyl analogues of GABA'Tetrahedron Asymmetry, 2004, 15, 1745-1751 [PDF]
Hall BJ, Chebib M, Hanrahan JR and Johnston GAR'Flumazenil-independent positive modulation of GABA action by6-methylflavone at human recombinant alpha1, beta2, gamma2L andalpha1, beta2 GABA-A receptors' European J. Pharmacology,2004, 491, 1-8 [PDF]
Henderson DJ, *Eberl S, *Thomson S, *Smith A, Allan RD, *FulhamMJ, *Loiacono R, Kassiou M. (2004) 3-Pyridyl ethers as SPECTradioligands for imaging nicotinic acetylcholine receptors. ApplRadiation and Isotopes. 60(5):669-76.
Huang SH , Duke RK, Chebib M, Sasaki K, Wada K and Johnston GAR,Ginkgolides, diterpene trilactones of Ginkgo biloba, asantagonists at recombinant alpha1, beta2, gamma2L GABA-A receptorsEuropean Journal of Pharmacology, 2004, 494, 131-138[PDF]
Johnston GAR and *Beart PM, 'Flavonoids: some of the wisdom ofsage?' British Journal of Pharmacology, 2004, 142,809-810 [PDF]
**Lee NA, **Wang S, Allan RD and **Kennedy IR (2004) A rapidaflatoxin B1 ELISA: development and validation with reduced matrixeffects for peanuts, corn, pistachio, and Soybeans. J Agric FoodChem., 2004 , 52, 2746-55.
Schliemer SB, Hinton T, Dixon G and Johnston GAR 'GABAtransporters GAT-1 and GAT-3 in the human dorsolateral prefrontalcortex in schizophrenia' Neuropsychobiology, 2004, 50,226-230 [PDF]
Chebib M, Duke RK, Connor M, Mewett KN and Johnston GAR 'Convulsant actions of calycanthine', Toxicology and AppliedPharmacology, 2003, 190, 58-64 [PDF]
Hanrahan JR, Chebib M, Davucheron NM, Hall BJ and Johnston GAR(2003) 'Semisynthetic preparation of amentoflavone: a negativemodulator at GABA-A receptors' Bioorganic & MedicinalChemistry Letters, 2003, 13, 2281-2284 [PDF]
**Hibbs DE, Hanrahan JR, **Hurtshouse MB, *Knight DW, **OvergaardJ, **Turner P, **Piltz RO and **Waller MP 'Experimental andtheoretical charge distribution in (Z)-N-methyl-C-phenylnitrone'Organic & Biomolecular Chemistry, 2003, 1,1034-1040
Huang SH, Duke RK, Chebib M, *Sasaki K, *Wada K and Johnston GAR'Bilobalide, a sesquiterpene trilactone from Ginkgo biloba, isan antagonist at recombinant a1b2g2LGABA-A receptors' European Journal of Pharmacology, 2003,464, 1-8 [PDF]
Johnston GAR 'Dietary chemicals and brain function' Journal& Proceedings of the Royal Society of New South Wales, 2003,135, 57-71 [PDF]
Johnston GAR, Chebib M, Hanrahan JR and Mewett KN 'GABA-Creceptors as drug targets' Current Drug Targets - CNS &Neurological Disorders, 2003, 2, 260-268 [PDF]
*Krehan D, *Frølund B, *Krogsgaard-Larsen, P, *Kehler J,Johnston GAR and Chebib M 'Phosphinic, phosphonic and seleninic acidbioisosteres of isonipecotic acid as novel and selective GABA-Creceptor antagonists' Neurochemistry International, 2003,42, 561-565 [PDF]
*Krehan D, *Frølund B, *Krogsgaard-Larsen, P, Johnston GARand Chebib M 'Aza-THIP and related analogues of THIP as GABA-Cantagonists', Bioorganic and Medicinal Chemistry, 2003,11, 4891-4896) [PDF]
**Waller MP, **Hibbs DE, Overgaard J, Hanrahan JR, **Hambley TW'Flavone' Acta Crystallographia, Section E. Structure ReportsOnline, 2003, E59, o767-768
Duke RK, Chebib M, Duke CC, Johnston GAR and Roufogalis BD 'Ginkgobiloba - food for the brain' New Zealand Pharmacy, 2002,22(5), 27-33 [PDF]
Johnston GAR 'Medicinal chemistry and molecular pharmacology ofGABA-C receptors' Current Topics in Medicinal Chemistry, 2002, 2, 903-913 [PDF]
*Topliss JG, *Clark AM, *Ernst E., *Hufford C, Johnston GAR ,*Rimoldi JM and *Weimann BJ 'Natural and synthetic substances relatedto human health (IUPAC Technical Report)', Pure and AppliedChemistry, 2002, 74, 1957-1985 [PDF]
Vien J, Duke RK, Mewett KN, Johnston GAR, *Shingai R and Chebib M,'trans-4-Amino-2-methylbut-2-enoic acid (2-MeTACA) and(±)-trans-2-aminomethylcyclopropanecarboxylic acid((±)-TAMP) can differentiate rat rho-3 from human rho-1 andrho-2 recombinant GABA-C receptors' British Journal ofPharmacology, 2002, 135, 883-890 [PDF]
Chebib M 'Novel agents acting on GABA-C receptors: potentialcognitive enhancers' Chemistry in Australia, 2001,68(9), 19-21
Chebib M, Duke RK, Allan RD and Johnston GAR 'The effects ofcyclopentane and cyclopentene analogues of GABA at recombinant GABA-Creceptors' European Journal of Pharmacology, 430,185-192 [PDF]
Dodds HM, Hanrahan JR and Rivory LP 'The inhibition ofacetylcholinesterase by irinotecan and related camptothecins: keystructural properties and experimental variables' Anti-cancer DrugDesign, 2001, 16, 239-249
Farrar NS, Chambers NJ, Carlsson AR, **Denyer G and Johnston GAR'Effect of a series of novel sulfonylthioureas on glucose tolerancein the obese fa/fa Zucker rat' Clinical and ExperimentalPharmacology and Physiology, 2001, 28, 386-391 [PDF]
Hall BJ, Hanrahan JR, Johnston GAR, **Hambley TW and Hibbs DE'6-Methylflavone" Acta Crystallographia, 2001, E57,o592-o593) (http://scripts.iucr.org/cgi-bin/paper?tk6019) [PDF]
Hanrahan JR, Mewett KN, Chebib M, Burden PM and Johnston GAR, Animproved, versatile synthesis of the GABA-C antagonists(1,2,5,6-tetrahydropyridin-4-yl)methylphosphinic acid (TPMPA) and(piperidin-4-yl)methylphosphinic acid (P4MPA) J. Chem. Soc.,Perkin Trans. 1, 2001, 19, 2389 -2392 [PDF]
Hanrahan JR, *Knight DW and *Salter R 'On the characteristics ofreverse-Cope cyclizations of homoallylic sulfoxide nitrone adducts: ahighly stereoselective route to pyrrolidine-N-oxides' Synlee,2001, 10, 1587-1589
Burden PM, Ai TH, Lin HQ, Akinci M, Costandi M, **HambleyTM and Johnston GAR 'Chiral derivatives of2-cyclohexylideneperhydro-4,7-methanoindenes, a novel class ofnonsteroidal androgen receptor ligand. Synthesis, X-ray analysis andbiological activity' Journal of Medicinal Chemistry, 2000,43, 4629-4635 [PDF]
Chebib M and Johnston GAR 'GABA-activated ligand gated ionchannels: medicinal chemistry and molecular biology' Journal ofMedicinal Chemistry, 2000, 43, 1427-1447 [PDF]
Chebib M and *Quinn RJ,'1-Phenylpyrazolo[3,4-d]pyrimidines: Structure-activityrelationships for C6 substituents at A1 and A2a Adenosine receptors'Bioorganic and Medicinal Chemistry, accepted 1.7.99
Duke RK, Chebib M, **Balcar VJ, Allan RD, Mewett KN and JohnstonGAR '(+)- and (-)-cis-2-Aminomethylcyclopropanecarboxylic acidshow opposite pharmacology at recombinant r1and r2 GABACreceptors' Journal of Neurochemistry, 2000, 75,2602-2610) [PDF]
Farrar N, 'New drug balances the diabetic see-saw' AustralasianScience, 2000, 21(9), 30-31
Johnston GAR 'The medicinal chemistry-molecular biology interface:recombinant receptors in the search for new drugs' in Technology& Health, Proceedings of the 13th Convocation of the Council ofAcademies of Engineering and Technological Sciences, ISBN2-7430-0386-3, Paris, France, 2000, pp 72-74
Johnston GAR 'GABA Chemistry: Analogs of GABA as therapeutic andinvestigational agents', in GABA in the Nervous System: The Viewat Fifty Years, Edited by David L. Martin and Richard W. Olsen,Lippincott Williams & Wilkins Publishers, Philadelphia, PA, USA,65-80
Johnston GAR, Chebib M, Duke RK 'Ionotropic GABA receptors: ligandgated ion channels' in Control and Diseases of Sodium DependentTransport Proteins and Ion Channels, Edited by Y Suketa, E Carafoli,M Lazdunski, K Mikoshiba, Y Okada and EM Wright, Elsevier Science,Amsterdam, The Netherlands, pp. 369-372, 2000
*Li Y, *Wood N, Grimsley P, *Yellowlees D and Donelly PK 'In vitroinvasiveness of human breast cancer cells is promoted by low densitylipoprotein receptor-related protein' Invasion Metastasis,2000, 18, 240-251
**Lieb I, Chebib M, **Cooper B, **Dias LS and **Balcar VJ,'Quantitative Autoradiography of Na+-dependent[3H]L-aspartate binding to L-glutamatetransporters in rat brain: Structure-activity studies usingL-trans-pyrrolidine-2,4-dicarboxylate (L-t-PDC) and2-(Carboxycyclopropyl)-glycine (CCG)', NeurochemistryInternational, 2000, 36, 319-327
Chebib M and Johnston GAR 'The ABC of GABA receptors: A briefreview', Clinical and Experimental Pharmacology and Physiology,1999, 26, 937-940 [PDF]
Chebib M, Johnston GAR, *Mattsson JP, *Rydström K, *NilssonK, *Qiu K, *Stevenson SH and *Silverman RB'Aminomethyl-2,6-difluorophenols as a novel class of increasedlipophilicity GABA-C receptor antagonists'Bioorganic &Medicinal Chemistry Letters, 1999, 9, 3093-3098 [PDF]
Cooper EJ, Johnston GAR and Edwards FA 'Effects of a naturallyoccurring neurosteroid on GABA-A IPSCs during development in rathippocampal or cerebellar slices' Journal of Physiology, 1999,521.2, 437-449 [PDF]
*Cordato DJ, Chebib M, *Mather LE, *Herkes GK and Johnston GAR,Stereoselective interaction of thiopentone enantiomers with theGABAA receptor, British Journal of Pharmacology,1999, 128, 77-82 [PDF]
Johnston GAR, Chebib M, Duke RK, Mewett KN, Mitrovic AD andVandenberg RJ, Medicinal chemistry and molecular pharmacology of GABAreceptors and glutamate transporters: complementarystructure-activity relationships, Drug Development Research,1999, 46, 255-260 [PDF]
Lin HQ, Burden PM, Christie MJ and Johnston GAR, 'Theanxiogenic-like and anxiolytic-like effects of MDMA on mice in theelevated plus maze: a comparison with amphetamine', Pharmacology,Biochemistry and Behavior, 1999, 62, 403-408 [PDF]
Mitrovic AD, Maddison JE and Johnston GAR, 'Influence of theoestrous cycle on L-glutamate and L-aspartate transport in rat brainsynaptosomes', Neurochemistry International, 1999, 34,101-108 [PDF]
*Wang S, Allan RD, *Skerritt JH and **Kennedy IR, 'Development ofa compound-specific ELISA for flufenoxuron and an improvedclass-specific assay for benzoylphenylurea insect growth regulators',Journal of Agricultural & Food Chemistry, 1999, 47,3416-3424
Burden PM, Allan RD, **Hambley T and Johnston GAR, 'The Synthesisof 2-Cyclohexylideneoctahydro-4,7-methano-1H-indenes. Non-SteroidalAnalogues of Steroidal GABAA Receptor Modulators',Journal of the Chemical Society, Perkin Transactions 1, 1998,3163-3169. [PDF]
Chebib M, Mewett KN and Johnston GAR, 'GABAC receptorantagonists differentiate between human rho1 and rho2 receptorsexpressed in Xenopus oocytes', European Journal ofPharmacology, 1998, 357, 227-234. [PDF]
**Cooper B, Chebib M, **Shen J, **King NJC, **Kuchel PW,*Rothstein JD and **Balcar VJ, 'Structural selectivity and molecularnature of L-glutamate transport in cultured human fibroblasts',Archives of Biochemistry and Biophyscis, 1998, 353,356-364.
Duke RK, Allan RD, Chebib M, Greenwood JR and Johnston GAR,'Resolution and conformational analysis of diastereoisomers ofcis- andtrans--2-(aminomethyl)-1-carboxycyclopropanes', TetrahedronAsymmetry, 1998, 9, 2533-2548. [PDF]
Greenwood JR, Vaccarella G, Capper HR, Allan RD and Johnston GAR(1998) "Heterocycles as bioisosteres for the w-carboxylatemoiety of glutamate in AMPA receptor agonists: A review andtheoretical study". Internet Journal of Chemistry 1, 38
Lin HG, Burden PM and Johnston GAR, 'Propylene glycol elicitsanxiolytic-like responses to the elevated plus maze in male mice',Journal of Pharmacy and Pharmacology, 1998, 50,1127-1131.
Mitrovic AD, *Amara SG, Johnston GAR and Vandenberg RJ,'Identification of functional domains of the human glutamatetransporters EAAT1 and EAAT', Journal of Biological Chemistry,1998, 273, 14698-14706. [PDF]
Vandenberg RJ, 'Molecular pharmacology and physiology of glutamatetransporters' Clinical and Experimental Pharmacology andPhysiology, 1998, 25, 393-400.
Vandenberg RJ, Mitrovic AD and Johnston GAR, 'Serine-O-sulfatetransport by the human glutamate transporter EAAT2', BritishJournal of Pharmacology, 1998, 123, 1593-1600. [PDF]
Vandenberg RJ, Mitrovic AD and Johnston GAR, 'Molecular basis fordifferential inhibition of glutamate transporter subtypes by zincions' Molecular Pharmacology, 1998, 54, 189-19.[PDF]
*Wang S, Allan RD, *Skerritt JH and **Kennedy IR 'Development of aclass-specific competitive ELISA for the benzoylphenylureainsecticides' Journal of Agricultural and Food Chemistry,1998, 46, 3330-3338.
Akinci MK and Johnston GAR 'Sex differences in the effects ofgonadectomy and acute swim stress on GABAA receptorbinding in mouse forebrain membranes', NeurochemistryInternational, 1997, 31, 1-10 [PDF]
Allan RD, Dickenson HW, Johnston GAR, Kazlauskas R and Mewett KN'Structural analogues of ZAPA as GABAA agonists',Neurochemistry International, 1997, 30, 583-59[PDF]
Chebib M and Johnston GAR 'Stimulation of [3-H]GABA and[3-H]beta-alanine release from rat brain slices bycis-4-aminocrotonic acid', Journal of Neurochemistry , 1997,68, 786-794 [PDF]
Chebib M and *Quinn RJ '1-Phenylpyrazolo[3,4-d]pyrimidinesas adenosine antagonists: the effects of substituents at C4 and C6',Bioorganic and Medicinal Chemistry, 5, 311-322
Chebib M, Vandenberg RJ, *Froestl W and Johnston GAR 'Unsaturatedphosphinic analogues of GABA as GABAC receptorantagonists', European Journal of Pharmacology, 1997,329, 223-239 [PDF]
Chebib C, Vandenberg RJ and Johnston GAR 'Analogues ofamma-aminobutryic acid (GABA) and trans--4-aminocrotonic acid (TACA)substituted in the 2 position as GABAC receptorantagonists', British Journal of Pharmacology, 1997,122, 1551-156 [PDF]
Greenwood JR, Capper HR, Allan RD and Johnston GAR 'Tautomerism ofhydroxy-pyridazines: the N-oxides', Journal of Molecular Structure(Theochem), 1997, 419, 97-11
Johnston GAR 'Cerebral chemistry', Chemistry in Australia,1997, 64(5), 34-36; reprinted in the AustralianChemistry Resource Book, 1997, 16, 67-72
Johnston GAR 'GABAC receptors: molecular biology,pharmacology and physiology'. In: The GABA Receptors, *EnnaSJ, *Bowery NG eds, 2nd edition, Humana Press, New Jersey, 1997,297-323
Maddalena DJ and *Snowdon GM 'Applications of genetic algorithmsto drug design', Expert Opinion in Therapeutic Patents, 1997,7, 247-254
Vandenberg R, Mitrovic A, Chebib M, **Balcar VJ and Johnston GAR'Contrasting modes of action of methylglutamate derivatives on theexcitatory amino acid transporters, EAAT1 and EAAT2', MolecularPharmacology, 1997, 51, 809-815 [PDF]
Allan RD, Duke RK, **Hambley TW, Johnston GAR, Mewett KN, QuickertN and Tran HW ; Synthesis of unsaturated analogues of glutamic acidby amination of trianions from unsaturated dicarboxylic acids withchloramine', Aust. J. Chem., 1996, 49, 785-79)
Cooper EJ, Johnston GAR and Edwards FA 'Differential sensitivityduring development of GABA-mediated synaptic transmission to aneuroactive steroid in rat hippocampus and cerebellum'. In GABA :Receptors, Transporters and Metabolism, edited by C. Tanaka andN.G. Bowery, Birkhäuser, Basel, 1996, pp. 195-200
Dodd P, Kril JJ, *Thomas GJ, Watson WEJ, Johnston GAR and **HarperCG 'Receptor binding sites and uptake activities mediating GABAneurotransmission in chronic alcoholics with Wernickeencephalopathy', Brain Research, 1996, 710, 215-228
Greenwood JR, Vaccarella G, Capper HR, Mewett KN, Allan RD andJohnston GAR 'Theoretical studies on the free-radical bromination ofmethyl-pyridazines in the synthesis of novel heterocyclic analoguesof neurotransmitters', Journal of Molecular Structure (Theochem),1996, 368, 235-243
Johnston GAR 'GABAA receptor pharmacology',Pharmacology & Therapeutics, 1996, 69, 173-198
Johnston GAR 'Small molecules as drugs',Chemistry inAustralia, 1996, 64, 212-213
Johnston GAR 'GABA-C receptors: relatively simpletrnasmitter-gated ion channels? Trends in PharmacologicalSciences, 1996, 17, 319-323 [PDF]
Maddison JE, Watson WEJ and Johnston GAR 'Synaptosomal and brainslice cerebrocortical 3H-L-glutamate uptake in a rat modelof hepatic encephalopathy', Neurochemistry International,1996, 28, 89-93
Allan RD, Apostopoulos C and **Hambley TW 'The synthesis andstructure of a cyclobutane analogue of glutamic acid with an aceticacid sidechain', Australian Journal of Chemistry, 1995,48, 919-928
Duke DK, Allan RD, **Duke CC, **Hambley TW, Johnston GAR, MewettKN and Mitrovic AD 'Idiospermuline, a trimeric pyrroldinoindolinealkaloid from the seed of Idiospermum australiense ',Journal of Natural Products Lloydia, 1995 58,1200-1208
Johnston GAR 'GABA receptor pharmacology'. In PharmacologicalSciences: Perspectives for Research and Therapy in the late 1990s,edited by AC Cuello and B Collier, Birkhäuser, Basel, 1995,pp. 11-15
Maddalena DJ and Johnston GAR 'Prediction of receptor propertiesand binding affinity of ligands to benzodiazepine/GABA-A receptorsusing artificial neural networks', Journal of MedicinalChemistry, 1995, 38, 715-724)
*Frydenvang K, *Krogsgaard-Larsen P, *Hansen JJ, Mitrovic A, TranH, Drew CA and Johnston GAR 'GABAB antagonists:resolution, absolute stereochemistry and pharmacology of (R)- and(S)-phaclofen, Chirality, 1994, 6, 583-589
Johnston GAR 'GABAC receptors', Progress in BrainResearch, 1994, 100, 61-65
Johnston GAR 'GABA receptors - as complex as ABC?', Clinicaland Experimental Pharmacology and Physiology, 1994, 21,521-526
Maddalena DJ and Johnston GAR 'Application of neural networks toquantitative structure-activity relationships ofbenzodiazepine/GABAA receptor binding compounds' In TheChallenge of Neuropharmacology, a Tribute to the Memory of WillyHaefely, edited by H. Möhler & M. Da Prada, EditionesRoche, Basel, 1994, pages 136-139
Mitrovic AD and Johnston GAR 'Regional differences in theinhibition of L-glutamate and L-aspartate sodium-dependent highaffinity uptake systems in rat CNS synaptosomes byL-trans-pyrrolidine-2,4-dicarboxylate,threo-3-hydroxy-D-aspartate and D-aspartate',Neurochemistry International, 1994, 24, 583-588
Akinci MK and Johnston GAR 'Sex differences in acute swim stressinduced changes in the binding of MK-801 to the NMDA subclass ofglutamate receptors in mouse forebrain ', Journal ofNeurochemistry, 1993, 61, 2290-2293)
Burden PM and Allan RD 'A facile synthesis of2-imino-1-pyrrolidinealkanoic acids', 1993, 23, 1195-1199
Dodd PR, Leong PR and Johnston GAR 'A Huntington Disease factorwhich inhibits [3H]kainate binding also blockssynaptosomal amino acid transport in rat brain', NeurochemistryInternational, 1993, 23, 131-13
Duke RK, Allan RD, Drew CA, Johnston GAR, Mewett KN, *Long MA and*Than C 'The preparation of tritiated E- andZ-4-aminobut-2-enoic acids, conformationally restrictedanalogues of the inhibitory neurotransmitter 4-aminobutanoic acid(GABA)', Journal of Labelled Compounds and Radiopharmaceuticals, 1993, 33, 527-540
Duke RK, Allan RD, Drew CA, Johnston GAR, Mewett KN, *Long MA and*Than C 'The synthesis and resolution of tritiated4-amino-3-phenylbutanoic acid ([3H]R- and[3H]S-beta-phenylGABA', Journal of LabelledCompounds and Radiopharmaceuticals, 1993, 33, 767-775
Capper HR, Mewett KN, Allan RD and Johnston GAR 'Molecularmodelling of N-methyl-D-aspartate (NMDA) receptor agonists andantagonists', Molecular Neuropharmacology, 1992, 2,83-87
Davies LP, Drew CA, *Duffield PM Johnston GAR and *Jamieson DD'Kava pyrones and resin: studies on GABAA,GABAB and benzodiazepine binding sites in rodent brain',Pharmacology & Toxicology, 1992, 71, 120-126)
Dodd PR, *Williams SH, Gundlach AL, *Harper PAW, *Healy PJ,*Dennis JA and Johnston GAR 'The glutamate and GABA neurotransmittersystems in the acute phase of maple syrup urine disease andcitrullinaemia encephalopathies in newborn calves', J.Neurochem., 1992, 59, 582-590)
Johnston GAR 'GABAA agonists as targets for drugdevelopment', Clinical and Experimental Pharmacology andPhysiology, 1992, 19, 73-78
Johnston GAR and Akinci MK 'Stress-induced changes inGABAA binding sites', Molecular Neuropharmacology,1992, 2, 151-154)
Allan RD, Dickenson HW, Duke RK and Johnston GAR 'ZAPA, asubstrate for the neuronal high affinity GABA uptake system in ratbrain slices ', Neurochemistry International, 1991, 18,63-67
Burden PM, Capper HR, Allan RD and Johnston GAR 'The synthesis of1,8-disubstituted 10,11-dihydrodibenz-[b,f]oxepin-10-ones.Analogues of anaesthetic steroids', J. Chem. Soc. Perkin Trans.1, 1991, 3291-3294
Fletcher EJ and Johnston GAR 'Regional heterogeneity ofL-glutamate and L-aspartate high affinity uptake systems in the ratCNS', J. Neurochem., 1991, 57, 911-914
Fletcher EJ, Mewett KN, Drew CA, Allan RD and Johnston GAR'Inhibition of high affinity L-glutamic acid uptake into rat corticalsynaptosomes by the conformationally restricted analogue of glutamicacid, cis-1-aminocyclobutane-1,3-dicarboxylic acid',Neuroscience Letters, 1991, 121, 133-135
Johnston GAR 'GABAA antagonists', Seminars in theNeurosciences, 1991, 3, 205-210
Maddison JE, Watson WEJ, Dodd PR and Johnston GAR 'Alterations incortical [3H]-kainate and[3H]-AMPA binding in a spontaneous animal model ofchronic hepatic encephalopathy ', J. Neurochem., 1991,56, 1881-1888
Allan RD and Apostopoulos C 'Synthesis of substituted(+)-bicuculline derivatives via chloromethylation', AustralianJournal of Chemistry, 1990, 43, 1259-1268
Allan RD, Apostoloulos C and Richardson JA'2-Imino-1,3,4-thiadiazole derivatives of GABA as GABAAantagonists', Australian Journal of Chemistry, 1990,43, 1767-1772
Allan RD, Bates MC, Drew CA, Duke RK, *Hambley TW, Johnston GAR,Mewett KN and Spence I 'A new synthesis, resolution and invitro activities of (R)- and (S)-beta-phenyl-GABA',Tetrahedron, 1990, 46, 2511-2524
Allan RD, Drew CA, Ong J and Tran HW 'Thioether analogues ofbaclofen, phaclofen and saclofen', Neuroscience Letters, 1990,112, 223-228
Allan RD, Hanrahan JR, **Hambley TW, Johnston GAR, Mewett KN andMitrovic AD 'Synthesis and activity of a potentN-methyl-D-aspartic acid agonist,trans--1-aminocyclobutane-1,3-dicarboxylic acid, and relatedphosphonic and carboxylic acids', Journal of MedicinalChemistry, 1990, 33, 2905-2915
Allan RD and Tran HW 'Facile synthesis of beta-phenylethylaminederivatives related to baclofen via aziridine ring opening',Australian Journal of Chemistry, 1990, 43,1123-1127
Bolden SW, Hambley JW, Johnston GAR and Rogers LJ 'Neonatal stressand long-term modulation of GABA receptors in rat brain'Neuroscience Letters, 1990, 111, 258-262
Dickenson HW, Duke RK, Balcar VJ, Allan RD and Johnston GAR'Binding to rat brain membranes of(+)-trans-(1S,3S)-3-aminocyclopentane-1-carboxylic acid,(+)-TACP, a selective GABA-A receptor agonist' MolecularNeuropharmacology, 1990, 1, 1-6)
Drew CA, Spence I and Johnston GAR 'Effect of chronic exposure tolead on GABA binding in developing rat brain' NeurochemistryInternational, 1990, 17, 43-51
Drew CA, Johnston GAR, Kerr DIB and Ong J 'Inhibition of baclofenbinding to rat cerebellar membranes by phaclofen, saclofen,3-aminopropylphosphinic acid and related GABA-A receptor antagonists'Neuroscience Letters, 1990, 113, 107-110
Gundlach AL, Grabara CSG, Johnston GAR and Harper PAW 'Receptoralterations associated with spinal motoneuron degeneration in bovineAkabane disease' Annals of Neurology, 1990, 27,513-519)
Huang JH and Johnston GAR'(+)-Hydrastine, a potent competitiveantagonist at mammalian GABA-A receptors' Brit. J. Pharmac.,1990, 99, 727-730
Johnston GAR ' Anxiety, steroids and GABA receptors' inAnxiety, N. McNaughton and G. Andrews, eds, University ofOtago Press, Dunedin, 1990, pp. 201-212)
Johnston GAR 'Anxiety chemistry' Chemistry in Australia,1990, 57, 334-337; reprinted in Australian ChemistryResource Book, 1991, 10, 15-21
Kerr DIB, Ong J and Johnston GAR 'Stress and cortisol modulationof GABA receptors' Stress & Anxiety, 1990, 13,209-213
Lummis SCR, Gundlach AL, Johnston GAR, Harper PAW and Dodd PR'Increased GABA receptor function in cerebral cortex of calves withan inherited deficit of spinal glycine/strychnine receptors' J.Neurochem., 1990, 55, 421-426
Maddison JE, Leong DK, Dodd PR and Johnston GAR, Plasma GABA-likeactivity in rats with hepatic encephalopathy is due to GABA andtaurine Hepatology, 1990, 11, 105-110
Ong J, Harrison NL, Hall RG, Barker JL, Johnston GAR and Kerr DIB'3-Aminopropanephosphinic acid is a potent agonist at peripheral andcentral presynaptic GABA-B receptors' Brain Research, 1990,526, 138-142)
Ong J, Kerr DIB, Capper HR and Johnston GAR 'Cortisone, a potentGABA-A antagonist in the guinea-pig isolated ileum' J. Pharm.Pharmacol., 1990, 42, 662-664)
Ong J, Kerr DIB, Johnston GAR and Hall RG 'Differing actions ofbaclofen and 3-amino-propylphosphinic acid in rat neocortical slices'Neuroscience Letters, 1990, 109, 169-173
Ong J, Kerr DIB and Johnston GAR 'Effects of potassium channelblockers on baclofen-induced suppression of paroxysmal discharges inrat neo-cortical slices' Neuroscience Letters, 1990,112, 216-222
**Member of another department, University of Sydney
*Not a member of the University of Sydney
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