About
Dr Dee Carter-
The ecology and population genetics of pathogenic fungi and symbiotic algae.
Elucidation of proteins involved in fungal pathogenesis
Summary
This project will investigate proteins up-regulated during mammalian infection by the fungal pathogen Cryptococcus.
Supervisor(s)
Research Location
School of Molecular and Microbial Biosciences
Program Type
Synopsis
Fungi cause a diverse range of diseases and are very difficult to treat. This project looks at proteins that are made by infectious fungi while they are causing disease in animal cells. Proteins made in particularly high abundance may be essential for the fungus to live and grow in animal tissues. By specifically targeting their production, it should be possible to stop the infection without harming the host cell. This information will therefore be used to design new antifungal drugs.
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Keywords
Cryptococcosis, mycosis, meningitis, pulmonary infection, Proteomics, Cryptococcus, yeast, pathogen, infection, Infectious diseases, Genes in biology & medicine, Infection & immunity
Opportunity ID
The opportunity ID for this research opportunity is: 122