Neural mechanisms that limit visual sensitivity

Summary

This research is concerned with how the brain analyses, and makes decisions about, the sensory information it receives. To understand this we study the visual system, the primary sense organ in primates, and the one that we know most about.

Supervisor(s)

Dr Sam Solomon

Research Location

Bosch Institute

Program Type

Masters/PHD

Synopsis

In physiological experiments we characterise at the level of nerve cells the work done by the eye and visual cortex. In perceptual experiments we explore performance, and compare these observations with the physiological ones through quantitative analysis.

In 2009 the lab is focusing on two important aspects of visual processing: the building blocks of human perception, particularly the appearance of form and colour. For example, we have shown that orientation perception in complex, nearly-natural, scenes may be understood in the framework of simple models, which may gives us a powerful method for predicting human perception in arbitrary situations.

The signals of nerve cells early in the visual pathway, particularly the responses of individual nerve cells, and the information carried by groups of nerve cells, by

1. measuring the responses of neurons in the middle temporal area (MT) to simple patterns and textures, to determine how these neurons provide signals for motion perception and eye movements

2. measuring the intracellular responses of neurons in the visual thalamus, to investigate the role of excitation and inhibition in determining how these neurons pass retinal signals to visual cortex.

Additional Information

Techniques used:Multi-channel in vivo electrophysiology, in vitro physiology (patch-clamping), psychophysics, human behaviour, computational modelling

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Keywords

Glaucoma, diabetes, Eye disease, Neurological disorders, Vision, Sensory Systems, cognition, Parallel Pathways, Brain & nervous system disorders, Hearing & vision problems, Neuroscience & psychology, The senses

Opportunity ID

The opportunity ID for this research opportunity is: 218