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Research Students
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Nathan Saul
Epidemiology of Cryptococcus gatti, a fatal pathogen of people and animals
I've investigated the case of a koala in New South Wales that presented with an unusually aggressive pathogen. I traced back the infecting strain to a koala park in Western Australia. By investigating the pathogen and the environmental associations, we can devise better prevention and treatment strategies.
Characterisation of canine adipose derived mesenchymal stem cells for treatment of diseases and disorders in dogs.
The application of regenerative medicine utilising adult stem cells in a developing area of veterinary science and this project proposes the characterisation of adipose derived canine mesenchymal stem cells which have successfully been utilised for the treatment of a number of disease and disorders in dogs.. more...
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Canine, mesenchymal stem cells, Veterinary science, Cell biology, regenerative medicine
Emerging parasitic disease: epidemiological, diagnostic and experimental approach
The project Emerging parasitic diseases: epidemiological, diagnostic and experimental approach will focus on development and elucidation of the epidemiology of newly or neglected disease in veterinary parasitology including (i) haemo- / tissue- parasites (Atoxoplasma, Babesia) and (ii) gastrointestinal parasites (Giardia, Cryptosporidium, Tritrichomonas).. more...
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Cryptosporidiosis, Giardiosis, Trichomonosis, Atoxoplasmosis, Babesisosis, Veterinary Medicine, Parasitology, Emerging Disease, Diagnostics, Infectious diseases, Infection & immunity
Immune mechanisms in resistance versus susceptibility to mycobacterial infection
The immune response to mycobacterial infection and the role of immune regulation in chronic disease will be examined using Johne’s disease (an internationally significant veterinary disease that has close parallels to human diseases including tuberculosis) as a model.. more...
Supervisor(s):
Whittington, Richard (Professor)
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Keywords:
Immune system, microbiology, mycobacteria, immune regulation, regulatory T cells, veterinary diseases, infection, immunity, inflammation, cytokines, gene expression, chronic disease, tuberculosis, Crohn’s., Infectious Disease, Chemokines
An investigation into symbiosis between virulent Rhodococcus equi and protozoa
Can virulent Rhodococcus equi replicate within protozoa found in the soil and gastrointestinal environment of the foal?. more...
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Masters/PHD
Keywords:
microbiology, virulent, Rhodococcus equi, protozoa, soil, gastro-intestinal environment, foal, horse, health, farm, facultative intracellular parasite, symbiosis, contamination, pulmonary, pneumonia, Macrophage, monoclonal antibodies, immunohistochemistry, PCR, qPCR, mAbs, VapA, veterinary, Infectious Disease, oral therapy, antiprotozoal
Bioinformatics approach to Cryptosporidium identity: database prospects
The Bioinformatics approach to Cryptosporidium identity: database prospects study will examine (i) the applicability of web based platform to clinical and field data and (ii) develop an automated approach to identification and annotation to sequences.. more...
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Cryptosporidiosis, Database, Bioinformatics, Nucleotide, genotyping, Parasitology, Emerging Disease, Diagnostics, Infectious diseases, Infection & immunity
Effects of Koala Retrovirus (KoRV) infection on the immune function of koalas and its potential role in causing immunosuppressive disease
This project will investigate the effects of KoRV infection on the immune function of koalas and its potential role in causing immunosuppressive disease by: a) Examining the effects of viral particles and peptides on the function of koala immune cells in-vitro; and b) Examining the prevalence and functional responses of relevant lymphocyte subsets in koalas with various states of KoRV infection and expression. We will also: c) Collect more detailed information to assess further the previously described trend for association between KoRV viral titre and chlamydial disease. more...
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Koala, Koala Retrovirus, KoRV, Marsupial Immunology, Wildlife Disease, Wildlife Health
Virulent Rhodococcus equi decontamination strategies on horse farms
An investigation into potential disinfectant agents that could be used on farms to reduce environmental virulent Rhodococcus equi burdens.. more...
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Masters/PHD
Keywords:
microbiology, equine, Infectious Disease, virulent, bacterial, farm, health, Thoroughbred, horse, disinfectants, Rhodococcus equi, decontamination, pneumonia, PCR analysis, spectrophotometer, safety, management practice, seasonal monitoring
Supplementation of probiotic fibrolytic enzymes to improve the utilisation of fibre by ruminants
The potency of exogenous cellulolytic enzymes as feed additive of ruminant has also been examined since late 1950s but it did not show any significance in improvement of the efficiency of feed utilization. more...
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Ruminant, nutrition, fibre, digestion, methane, microbial, protein, synthesis, in vitro, in vivo, in situ, overseas travel; international collaboration; animal science; ruminant nutrition.
Using the fuel crisis to relieve the drought: an evaluation of distillers grains as an environmentally sustainable ruminant feed
The production of ethanol from cereal grains is not a new process and the resulting by-product, dried distillers grains with solubles (DDGS) have been included in ruminant rations for many years. Ethanol was the fuel of choice for the Ford Model T in the early 1900s and research utilizing distillers grains is recorded as early as 1894. However gasoline was cheap then; today the prices of crude oil are increasing significantly and research is developing new substitute, renewable fuel sources. Over the past 10 years, over 100 ethanol distillation plants have been built in the Midwestern USA to increase renewable bio-ethanol production.Ethanol production requires the fermentation of starch; therefore, with the starch removed the DDGS by-product is a concentrated feedstuff of the parent cereal grain. As a result, DDGS is high in protein, digestible neutral detergent fibre and some minerals such as phosphorus and sulphur. The objectives of this project are to determine the effect replacing grain and or fibre source in the diet with dry distillers’ grains with solubles on: Apparent digestibility and nutrient excretion in ruminants fed concentrate diets;Feed intake, gain, feed efficiency, and carcass yields in lambs as well as beef cattle fed concentrate diets;Identification of the level of DDGS which may replace dietary components in the ruminant diets and verify lamb/cattle performance and sustainability.. more...
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Industry by-products, ruminant nutrition, animal performance, carcass evaluation, meat/milk quality, sustainable production systems
Nematode virulence proteomics as worm resistance markers in sheep
Worm components which enhance infectivity may be targets for neutralisation by host defences and the reaction may be exploited as a marker to identify resistant and susceptible sheep.. more...
Supervisor(s):
Emery, David (Associate Professor)
Research Location:
Department of Parasitology, Veterinary Science
Program Type:
Masters/PHD
Keywords:
Gastrointestinal parasites, nematodes, parasite resistance, Parasites, immunity, resistance, sheep, Infectious diseases, Infection & immunity